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In some cases, patients may be deficient in the vitamin and suffering related symptoms, while in others, B12 may be considered potentially helpful in preventing or treating certain conditions

[49] B 12 is required by enzymes for two reactions: the conversion of methylmalonyl-CoA to succinyl-CoA, and the conversion of homocysteine to methionine

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Last year I met with the editor of the British National Formulary (BNF) to discuss the problems that a great many of our members have in receiving adequate replacement therapy injection based on their individual needs

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